This year’s winning entry arose from Cisterna’s research into a protein crucial for building brain cell structure (profilin 1, or PFN1); that structure is essential for functional cellular transport. He found that when the protein and related processes are disrupted, the microtubule highways can malfunction and cause damage to the cells. Capturing the actin, microtubules, and nuclei with photomicroscopy was a painstaking process that took about three months just to perfect the staining process. Cisterna and Vitriol paid particular attention to getting just the right field of view and got the image they were waiting for after three hours of observation.
“At 50 years, Nikon Small World is more than just an imaging competition—it’s become a gallery that pays tribute to the extraordinary individuals who make it possible,” said Nikon Instruments rep Eric Flem. “They are the driving force behind this event, masterfully blending science and art to reveal the wonders of the microscopic world and what we can learn from it to the public. Sometimes, we overlook the tiny details of the world around us. Nikon Small World serves as a reminder to pause, appreciate the power and beauty of the little things, and to cultivate a deeper curiosity to explore and question.”
Here are the remaining top 20 winners of this year’s contest, ranging from close-up views of octopus eggs, green crab spider eyes, and slime molds to capturing the electric arc between a pin and wire, and an insect egg that has been parasitized by a wasp. You can check out the full list of winners, as well as several honorable mentions, here.
And the winners are …
Second place: Electrical arc between a pin and a wire.
Marcel Clemens/Nikon Small World
Second place: Electrical arc between a pin and a wire.
Marcel Clemens/Nikon Small World
Third place: Leaf of a cannabis plant. The bulbous glands are trichomes. The bubbles inside are cannabinoid vesicles.
Chris Romaine/Nikon Small World
Third place: Leaf of a cannabis plant. The bulbous glands are trichomes. The bubbles inside are cannabinoid vesicles.
Chris Romaine/Nikon Small World
Fourth place: Section of the small intestine of a mouse.
Amy Engevik/Nikon Small World
Fourth place: Section of the small intestine of a mouse.
Amy Engevik/Nikon Small World
Third place: Leaf of a cannabis plant. The bulbous glands are trichomes. The bubbles inside are cannabinoid vesicles.
Chris Romaine/Nikon Small World
Fourth place: Section of the small intestine of a mouse.
Amy Engevik/Nikon Small World
Fifth place: Cluster of octopus (Octopus hummelincki) eggs.
Thomas Barlow & Connor Gibbons/Nikon Small World
Sixth place: Slime mold (Cribraria cancellata).
Henri Koskinen/Nikon Small World
Seventh place: Cross section of European beach grass (Ammophila arenaria) leaf.
Gerhard Vlcek/Nikon Small World
Eighth place: A neuron densely covered in dendritic spines from the striatum of an adult rat brain.
Stephanie Huang/Nikon Small World
Ninth place: Pollen in a garden spider (Araneus) web.
John-Oliver Dunn/Nikon Small World
10th place: Spores of black truffle (Tuber melanosporum).
Jan Martinek/Nikon Small World
11th place: Slime mold on a rotten twig with water droplets.
Ferenc Halmos/Nikon Small World
12th place: Wing scales of a butterfly (Papilio ulysses) on a medical syringe needle.
Daniel Knop/Nikon Small World
13th place: Eyes of green crab spider (Diaea dorsata).
Patel Blachowicz/Nikon Small World
14th place: Recrystallized mixture of hydroquinone and myoinositol.